Product Information: Docetaxel
Docetaxel
| Cat. No. | HXO-11300 |
|---|---|
| CAS. No. | 114977-28-5 |
| Category | API Standards |
| Stock Status | Instock |
| Molecular Formula | C43H53NO14 |
| Molecular Weight | 807.88 mol/g |
| Application | "Docetaxel is a semi-synthetic, second-generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and cell death. This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Docetaxel has been studied for use as a radiation-sensitizing agent." |
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